Eculizumab is a first-in-class terminal complement inhibitor which works by electively inhibiting activation of specific proteins in the complement system (c5 and c5b), which play a role in the treatment of multiple rare diseases.
Nufactor carries the following eculizumab brand:
- Soliris® (Alexion)
- Generalized myasthenia gravis (adult)
- Neuromyelitis Optica Spectrum Disorder (adult)
- Atypical hemolytic uremic syndrome
- Paroxysmal nocturnal hemoglobinuria
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