Hypogammaglobulinemia is an immune disorder characterized by an abnormally low level of immunoglobulin type G (IgG) in the blood, resulting in increased risk of infection. People diagnosed with non-specific types of immune deficiencies may not meet the strict diagnostic criteria for other deficiencies (e.g, CVID) but still have low levels of IgG and lack of functional antibodies.
Symptoms of Hypogammaglobulinemia
Patients with hypogammaglobulinemia present a history of recurring infections.
Various laboratory and imaging studies may be helpful in diagnosing hypogammaglobulinemia. Having a low IgG level may not always be related to immune deficiency but may be caused by another condition such as a kidney or gastrointestinal condition, cancer or severe burns, or may be related to medication such as long term use of corticosteroids.
When other conditions or medications causing the reduction of IgG are ruled out, immune globulin replacement therapy administered into the blood stream intravenously (IVIG) or under the skin subcutaneously (SCIG) is the preferred treatment for hypogammaglobulinemia.
This content is not intended to substitute professional medical advice. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
At Nufactor, we are committed to providing our patients the education, support and resources necessary to complete your IVIG treatment successfully and with the desired outcomes. Please contact us with any further questions.