Diagnoses & Conditions

Ankylosing Spondylitis

Understanding Ankylosing Spondylitis

Ankylosing Spondylitis (AS) is a form of arthritis affecting the spine (other joints can become involved). AS causes inflammation of the spinal joins (vertebrae) and can lead to chronic pain and discomfort.

Symptoms of Ankylosing Spondylitis

Symptoms of AS include frequent pain and stiffness in the lower back and buttocks area. These symptoms arise gradually within a few weeks or months. It begins on one side, or the sides alternate and is typically stronger in the mornings and during the night. Additionally in the earlier stages of AS, symptoms include mild fever, loss of appetite and overall discomfort. For most, the pain typically becomes chronic and is felt on both sides over the course of three months.

Diagnosing Ankylosing Spondylitis

Diagnosing AS includes a thorough physical exam and individual as well as family history, x-rays and blood tests.

Treating Ankylosing Spondylitis

FDA-approved drugs commonly prescribed to reduce signs and symptoms of AS include infliximab (e.g., Inflectra®, Remicade®) and golimumab (Simponi Aria®), administered into the blood stream intravenously. Also FDA-approved, golimumab (Simponi®) is administered under the skin subcutaneously.

This content is not intended to substitute professional medical advice. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.


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