Immune globulins are antibodies that are part of the immune system. Antibodies are produced by a complex series of interactions between white blood cells called B and T lymphocytes. Immune globulin is made from thousands of pooled human plasma donations. To prevent transmission of any blood-borne viruses or diseases, donors are carefully screened, and the donated plasma is tested to ensure it does not contain any pathogens.
Among the several manufacturers of IVIG and SCIG, each one uses a slightly different process to separate the antibodies from the plasma, so each brand is different. These differences may result in patients tolerating one brand better than another (Learn about the different brands here ).
About IVIG Administration
Intravenous immune globulin (IVIG) is administered into a vein, typically in a patient’s arm. The infusion is started very slowly and gradually increased to a predetermined maximum rate to lessen side effects. Infusion times vary from person to person and should be determined by your doctor or pharmacist.
About SCIG Administration
Subcutaneous immune globulin (SCIG) can be administered intravenously or subcutaneously. SCIG is administered under the skin into subcutaneous tissue. The best sites for SCIG are the abdomen, the tops of the thighs and the backs of the upper arms. Multiple sites may be required for one infusion, and infusion times vary from person to person. The right number of infusion sites and length of infusion will be determined by the doctor and pharmacist, based on how the infusion is tolerated.
At NuFACTOR, we are committed to providing our patients all of the education, support and resources necessary to complete treatment successfully and with the desired outcomes. Please contact us with any further questions.